One of the stories of the year has been the stark underperformance of ASX healthcare shares.
As the calendars turn over to June, the S&P/ASX 200 Health Care Index (ASX: XHJ) sits almost 33% lower than at the start of the year.
This makes it the worst performing sector in 2026 by some margin.
ASX healthcare shares have been hit by a combination of earnings downgrades, rising cost pressures, weaker overseas earnings and investor concerns that growth across the sector is slowing.
Because healthcare makes up a large part of the Australian market's growth-stock universe, higher interest rates and a strong rotation into energy, mining, and resource stocks have amplified the sell-off.
For investors, this could be an intriguing opportunity to gain exposure to quality companies at a historic discount.
Here are three of the largest ASX healthcare stocks that are tipped to rebound from historic lows.
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Pro Medicus Ltd (ASX: PME)
Pro Medicus enjoyed a fast start to the month of June.
The medical imaging technology company rose over 9% yesterday following a key contract win.
Investors will be hoping this is the start of a long-term rebound.
Despite yesterday's 9% gain, it remains down 35% year to date.
It closed yesterday at $144.46 per share.
However brokers are confident it will rise significantly higher in the next 12 months.
13 analysts offering a one year forecast have an average price target of $187.27 on Pro Medicus shares, indicating roughly 3% upside from current levels.
11 of the 13 analysts rate the stock as a strong buy or buy.
ResMed Inc (ASX: RMD)
While Pro Medicus shares started June off with a big rise, it was the opposite start to the month for ResMed shares.
ResMed is a global leader in sleep technology.
Its share price fell more than 7% yesterday, and is now down 26% year to date.
It now sits at a new 52-week low of $26.27.
However this could now be a rare opportunity to scoop up this ASX healthcare stock at a significant value.
Morgans expects a rebound over the next 12 months. The broker has a price target of $41.72 along with a buy rating.
This indicates an upside potential of almost 59%.
Sonic Healthcare Ltd (ASX: SHL)
It has been a similarly difficult 2026 for Sonic Healthcare shares.
Its share price is down more than 14% year to date.
However the global healthcare provider could also be set to recover in the near term.
12 analysts forecasts via TradingView have an average one year price target of $23.40 on this ASX healthcare stock.
This indicates an upside potential of 21% from current levels.
