These are the 10 most shorted ASX shares

Let's see which shares short sellers are targeting this week.

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At the start of each week, I like to look at ASIC's short position report to find out which shares are being targeted by short sellers.

This is because I believe it is well worth keeping a close eye on short interest levels as high levels can sometimes be a sign that something isn't quite right with a company.

With that in mind, here are the 10 most shorted shares on the ASX this week according to ASIC:

  • Domino's Pizza Enterprises Ltd (ASX: DMP) continues its run as the most shorted ASX share after its short interest rose slightly to 15.3%. It seems that short sellers are betting against the pizza chain operator's turnaround strategy.
  • Telix Pharmaceuticals Ltd (ASX: TLX) has short interest of 14.3%, which is down slightly since last week. This radiopharmaceuticals company failed to gain FDA approval for a couple of its therapies last year. Short sellers don't appear confident that 2026 will be any better despite a recent resubmission.
  • Polynovo Ltd (ASX: PNV) has short interest of 14.2%, which is flat since last week. This may be due to valuation concerns with the medical device company's shares trading on high earnings multiples.
  • Guzman Y Gomez Ltd (ASX: GYG) has short interest of 14.1%, which is up week on week. This quick service restaurant operator's shares have fallen heavily over the past 12 months due to their premium valuation and concerns that its US expansion could be a failure. The US was supposed to be its largest growth opportunity.
  • Boss Energy Ltd (ASX: BOE) has short interest of 12.1%, which is up again since last week. There are major concerns over this uranium miner's production outlook beyond 2026.
  • Treasury Wine Estates Ltd (ASX: TWE) has seen its short interest fall again to 11.6%. This wine giant is battling consumer spending pressures and distributor disruption. Short sellers appear to believe it will get worse before it gets better.
  • Nanosonics Ltd (ASX: NAN) has entered the top ten with short interest of 11.8%. This infection prevention technology company's performance has underwhelmed in recent times. It seems that short sellers aren't confident a change is coming.
  • Flight Centre Travel Group Ltd (ASX: FLT) has short interest of 11.8%, which is up week on week again. Short sellers have been loading up on the travel agent's shares since the Middle East conflict. There are concerns it could have a negative impact on travel markets.
  • DroneShield Ltd (ASX: DRO) has 11.4% of its shares held short, which is up since last week. Short sellers appear to think this counter drone technology company's shares are overvalued after surging over the past 12 months.
  • Lotus Resources Ltd (ASX: LOT) has short interest of 10.2%. This uranium producer is one of a number of stocks in the industry being targeted by short sellers, with several sitting just outside the top ten.

Motley Fool contributor James Mickleboro has positions in Domino's Pizza Enterprises and Treasury Wine Estates. The Motley Fool Australia's parent company Motley Fool Holdings Inc. has positions in and has recommended Domino's Pizza Enterprises, DroneShield, PolyNovo, Telix Pharmaceuticals, and Treasury Wine Estates and is short shares of DroneShield. The Motley Fool Australia has positions in and has recommended Treasury Wine Estates. The Motley Fool Australia has recommended Domino's Pizza Enterprises, Flight Centre Travel Group, PolyNovo, and Telix Pharmaceuticals. The Motley Fool has a disclosure policy. This article contains general investment advice only (under AFSL 400691). Authorised by Scott Phillips.

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