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At the start of each week, I like to look at ASIC's short position report to find out which shares are being targeted by short sellers.
This is because I believe it is well worth keeping a close eye on short interest levels as high levels can sometimes be a sign that something isn't quite right with a company.
With that in mind, here are the 10 most shorted shares on the ASX this week according to ASIC:
- Domino's Pizza Enterprises Ltd (ASX: DMP) continues to be the most shorted ASX share with short interest of 16%. This is up week on week. Short sellers appear doubtful that the struggling pizza chain operator's turnaround strategy will be a success.
- Telix Pharmaceuticals Ltd (ASX: TLX) has short interest of 15.3%, which is up again since last week. This radiopharmaceuticals company has been struggling with FDA approvals. It seems that short sellers don't believe regulators will be approving its therapies any time soon.
- Treasury Wine Estates Ltd (ASX: TWE) has seen its short interest rise again to 15.1%. This wine giant has been battling very tough trading conditions, with consumers focusing on value rather than its premium wines.
- Guzman Y Gomez Ltd (ASX: GYG) has short interest of 13.4%, which is down week on week. This may be due to the burrito seller struggling the United States market, which was supposed to be its largest growth opportunity.
- Polynovo Ltd (ASX: PNV) has short interest of 13.3%, which is up again since last week. This medical device company's shares trade with a premium valuation.
- Nanosonics Ltd (ASX: NAN) has 11.7% of its shares held short, which is up week on week again. This infection prevention company's performance has been underwhelming in FY 2026, with profit before tax falling 3% during the first half.
- Boss Energy Ltd (ASX: BOE) has short interest of 11.2%, which is down since last week. Short sellers continue to close positions in the uranium producer, which was the most shorted ASX share for much of 2025.
- IDP Education Ltd (ASX: IEL) has 10.7% of its shares held short, which is down week on week again. Short sellers have been targeting this student placement and language testing company due to unfavourable changes to visa rules in key markets.
- Lynas Rare Earths Ltd (ASX: LYC) has short interest of 10.5%, which is flat week on week. This is likely due to valuation concerns after the rare earths producer's shares rocketed over the past 12 months.
- Flight Centre Travel Group Ltd (ASX: FLT) has short interest of 10.3%, which is up week on week. There are concerns that the travel agent won't deliver on its revenue margin targets, especially given how the war in the Middle East could impact travel markets.