3 high-conviction ASX 200 stocks to buy and hold

Brokers think these shares are among the best to buy now.

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If you're looking to build serious long-term wealth on the share market, ASX 200 stocks with sustainable competitive advantages and scalable business models should be high on your watchlist.

Here are three standout stocks with the potential to deliver substantial shareholder value over the coming years.

Pro Medicus Ltd (ASX: PME)

Pro Medicus is no stranger to ASX success stories. The medical imaging software company has carved out a global niche in radiology tech, helping hospitals and healthcare providers improve diagnostic workflows and data handling with its flagship product, Visage.

What sets Pro Medicus apart is its razor-sharp focus on high-end imaging and long-duration contracts with top-tier hospitals. This isn't just about selling software — it's about becoming an indispensable part of a hospital's tech stack.

With an incredibly strong balance sheet, global expansion runway, and recurring revenue model, this ASX 200 stock remains a high-conviction pick for growth-focused investors.

Morgan Stanley has an overweight rating and $310.00 price target on its shares.

Life360 Inc (ASX: 360)

Life360 has been quietly transforming from a family safety app into a data-rich ecosystem with immense monetisation potential. The company has enjoyed a stellar run lately, surging in recent months to become one of the ASX's standout tech performers.

Its appeal lies in its sticky user base and optional premium features that users are increasingly willing to pay for. With expansion into new geographies and growing synergies from its acquisition of Jiobit and Tile, Life360 is evolving into a robust consumer tech business with a strong moat.

If it can continue to grow its average revenue per user and paid user numbers, the upside over the next five to ten years could be significant.

Morgan Stanley is also positive on this one. It has an overweight rating and $40.00 price target on its shares.

NextDC Ltd (ASX: NXT)

A final ASX 200 stock that is rated very highly is NextDC. It continues to be one of the ASX's most compelling long-term growth stories. As the backbone of Australia's cloud infrastructure, NextDC owns and operates some of the country's most advanced data centres.

With enterprise and government demand for secure, high-availability data storage growing rapidly — particularly with AI, machine learning, and hybrid cloud deployments — the company is well placed to capture this structural trend.

The company's data centre footprint is expanding, with new facilities under development in Melbourne, Sydney, and the Asia-Pacific region to meet surging demand. And as businesses continue to digitise and the AI arms race heats up, NextDC offers leveraged exposure to a secular mega trend in digital infrastructure.

Macquarie is bullish on NextDC. The broker has an outperform rating and $22.10 price target on its shares

Motley Fool contributor James Mickleboro has positions in Life360, Nextdc, and Pro Medicus. The Motley Fool Australia's parent company Motley Fool Holdings Inc. has positions in and has recommended Life360 and Macquarie Group. The Motley Fool Australia's parent company Motley Fool Holdings Inc. has recommended Pro Medicus. The Motley Fool Australia has positions in and has recommended Macquarie Group. The Motley Fool Australia has recommended Pro Medicus. The Motley Fool has a disclosure policy. This article contains general investment advice only (under AFSL 400691). Authorised by Scott Phillips.

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