3 ASX 200 shares for smart investors to buy and hold

Not sure where to invest? Here are three smart picks for January.

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Smart investing is not about finding the most exciting stock in the market.

More often, it comes down to owning high-quality businesses that can stay relevant, keep reinvesting effectively, and compound value over long periods of time. These are the ASX 200 shares that tend to justify being held through market cycles.

With that in mind, here are three ASX 200 shares that smart, long-term investors may want to consider buying and holding.

CSL Ltd (ASX: CSL)

CSL is a business built around scale, expertise, and long-term investment.

The biotechnology company's global plasma collection and manufacturing network is not something that can be replicated quickly or cheaply. That infrastructure advantage gives CSL a strong competitive position and allows it to serve growing demand for plasma-derived therapies worldwide.

What makes CSL particularly attractive for buy and hold investors is its research and development investments. Rather than maximising short-term capital returns, the company consistently channels capital into advancing research. Over time, that approach has translated into steady earnings growth and resilience across very different market environments.

So, with its shares down heavily from their highs, now could be an opportune time to buy a quality company at a discount.

ResMed Inc. (ASX: RMD)

ResMed operates in a corner of healthcare where demand is driven by long-term trends.

Sleep apnoea and respiratory conditions are becoming more widely diagnosed as awareness improves and populations age. ResMed benefits from this through a combination of medical devices, masks, and software platforms that support patient monitoring and compliance.

In addition, ResMed is increasingly becoming a digital healthcare company. It uses data and connected devices to deepen relationships with providers and patients. This shift supports recurring revenue and strengthens customer stickiness over time.

Overall, I think ResMed offers exposure to healthcare innovation with a proven commercial foundation.

Xero Ltd (ASX: XRO)

A final ASX 200 share to buy and hold could be Xero. Its cloud-based accounting platform has become integral for millions of small businesses and their advisers. Once adopted, it is not easily replaced, which supports long-term customer retention and recurring revenue.

Xero is still expanding its addressable market. International growth, particularly in large regions like the United States and the United Kingdom, provides it with a long growth runway. At the same time, ongoing product development and acquisitions allow Xero to increase the value it delivers to existing customers.

In light of this, I believe Xero represents a company that can keep growing long into the future. And this is exactly what you want from a buy and hold investment.

Motley Fool contributor James Mickleboro has positions in CSL, ResMed, and Xero. The Motley Fool Australia's parent company Motley Fool Holdings Inc. has positions in and has recommended CSL, ResMed, and Xero. The Motley Fool Australia has positions in and has recommended ResMed and Xero. The Motley Fool Australia has recommended CSL. The Motley Fool has a disclosure policy. This article contains general investment advice only (under AFSL 400691). Authorised by Scott Phillips.

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