3 ASX 200 blue-chip shares I would buy with $100,000

If I had $100,000 to invest today, I'd back proven blue chips built to endure and compound through market cycles.

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If I were deploying $100,000 into the share market today, I'd focus on simplicity, durability, and businesses that have already proven they can compound value through multiple cycles.

With that mindset, here are three ASX 200 blue-chip shares I would be comfortable backing with a meaningful amount of capital.

CSL Ltd (ASX: CSL)

CSL is the definition of a blue chip on the Australian share market.

After a disappointing 2025, expectations for CSL are far more grounded in 2026 than in previous years. The market has already repriced the stock to reflect slower near-term growth in its plasma therapies business and softer conditions in vaccines. That reset matters.

What hasn't changed is CSL's competitive position. It remains one of just three global tier-one plasma therapy companies, operating in an oligopolistic market with enormous barriers to entry.

As plasma efficiency initiatives progress and margins begin to recover over the coming years, CSL's earnings growth should normalise. 

It doesn't need to surprise on the upside; it just needs to execute steadily. For a $100,000 portfolio, I think it could be a core holding.

Wesfarmers Ltd (ASX: WES)

Wesfarmers is a stock I turn to when I want resilience without stagnation.

The company owns some of Australia's strongest consumer brands, including Bunnings, Kmart, Officeworks, and Priceline. These are businesses with scale, pricing power, and entrenched market positions. They generate significant cash flow across a wide range of economic conditions.

What sets Wesfarmers apart from many other ASX 200 blue-chip shares is management's capital discipline. The company has shown a consistent willingness to rework its portfolio, exit underperforming assets, and reinvest where long-term returns look attractive. That mindset is critical for compounding over decades.

Wesfarmers may not deliver explosive growth in any single year, but it offers diversification, downside protection, and steady value creation. If I were investing $100,000, I'd want at least one stock that helps me sleep well at night. For me, that's Wesfarmers.

Macquarie Group Ltd (ASX: MQG)

Macquarie is not a traditional bank, and that's precisely why I like it.

The company operates across asset management, banking, commodities, capital markets, and advisory services. This diversified model enables Macquarie to generate earnings across various market environments, rather than relying on a single economic outcome.

Over time, Macquarie has proven its ability to allocate capital patiently, manage risk conservatively, and pivot its business mix as opportunities evolve. Its asset management division, in particular, provides exposure to long-term themes such as infrastructure, energy transition, and global investment flows.

Macquarie's earnings can fluctuate year to year, but the long-term trajectory has been consistently upward. For investors with a large sum to invest, I think that combination of diversification and optional upside makes it an attractive blue-chip holding.

Foolish Takeaway

CSL, Wesfarmers, and Macquarie are not speculative ideas. They are established, well-managed businesses with competitive advantages and long track records of navigating uncertainty.

If I were investing $100,000 today, I'd be backing companies that have already proven they can endure, adapt, and compound. These three blue chips tick those boxes for me.

Motley Fool contributor Grace Alvino has positions in CSL and Wesfarmers. The Motley Fool Australia's parent company Motley Fool Holdings Inc. has positions in and has recommended CSL, Macquarie Group, and Wesfarmers. The Motley Fool Australia has positions in and has recommended Macquarie Group. The Motley Fool Australia has recommended CSL and Wesfarmers. The Motley Fool has a disclosure policy. This article contains general investment advice only (under AFSL 400691). Authorised by Scott Phillips.

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