A $2,000 investment may not sound like a life-changing amount of money.
But I think it can still be a very useful starting point if it is put into high-quality ASX shares and left to compound.
For me, the best approach would be to focus on businesses with strong positions in attractive markets. I would want companies that can keep getting larger over time.
Three blue-chip ASX shares I would happily buy with $2,000 are named in this article.

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Sigma Healthcare Ltd (ASX: SIG)
Sigma Healthcare has become a much more interesting company since merging with Chemist Warehouse.
The business now gives investors exposure to a powerful pharmacy retail network, healthcare distribution, and the long-term demand for medicines, wellness products, and everyday health-related spending.
That combination appeals to me. Healthcare retail has some defensive qualities because people still need prescriptions, over-the-counter products, and pharmacy services in most economic environments. But Sigma also has a growth side because Chemist Warehouse is a highly recognisable brand with a large customer base and potential to keep expanding.
I think the scale of the combined business is important. A larger network can help with supplier relationships, distribution efficiency, data, marketing, and customer reach.
The valuation may not always look cheap, and integration still needs to be handled well. But if the merged group can keep executing, I think Sigma could be a great long-term investment.
REA Group Ltd (ASX: REA)
REA Group is another blue-chip ASX share I would consider buying with $2,000.
The company owns realestate.com.au, which sits at the centre of Australia's property search market.
I like REA because it has a rare position in an area that attracts huge consumer attention. Australians care deeply about property. Buyers browse listings, sellers want maximum exposure, agents need leads, and advertisers want access to that audience.
REA connects all of those groups. This creates a powerful network effect. Buyers and renters go where the listings are. Agents want to list where the buyers and renters are. That loop helps protect REA's position.
The stock often trades on a premium valuation, which means investors should be comfortable paying for quality. But I think dominant digital platforms with strong brands and high margins deserve close attention when building a long-term portfolio.
Wesfarmers Ltd (ASX: WES)
Wesfarmers is a third ASX blue-chip share I would be happy to own for the long term.
The group has built a collection of businesses that reach into many parts of Australian consumer life. Bunnings remains a standout in home improvement, Kmart has become a powerful value-focused retailer, Officeworks serves households and businesses, and Priceline gives the group exposure to health and beauty.
I think that mix is useful in the current environment. Households may be under pressure, but they still need everyday products, affordable clothing, home essentials, school supplies, medicines, and health-related items. Wesfarmers has brands that can stay relevant across those needs.
The share price can still be affected by consumer confidence, costs, and valuation. But I think Wesfarmers has enough quality across the group to keep compounding over time.
Foolish takeaway
A $2,000 investment will not transform a portfolio overnight.
But I think it can still be put to work in a way that makes sense for the long term.
Sigma, REA Group, and Wesfarmers all have strong positions in areas where demand is likely to remain important: healthcare retail, property search, and everyday household spending.
That is the kind of foundation I would want from blue-chip ASX shares. The returns may take time to show up, and the entry price still matters, but I would be very comfortable letting these three businesses work away in the background for years.