After falling 22% in August, is this ASX 100 star the best share to buy today?

Profits are up, shares are down. Is this market darling primed for a rebound?

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When an ASX heavyweight stumbles, investors often ask the same question: Is it a red flag or a rare chance to buy quality at a discount?

That's the dilemma facing shareholders of CSL Ltd (ASX: CSL). The healthcare leader shocked the market last month when its share price tumbled almost more than 22% from peak to trough, wiping billions from its market value.

So, what went wrong and could this be a golden opportunity in disguise?

What triggered the sell-off?

CSL delivered its full-year FY25 results in August, reporting a 5% rise in revenue to US$15.6 billion and a 17% lift in net profit after tax to US$3 billion. On the surface, those are solid numbers.

However, investors were caught off guard by news that CSL will demerge its Seqirus vaccine division, reshaping the company's portfolio. While the move could sharpen CSL's focus on plasma therapies and innovation, the uncertainty around execution rattled markets.

The result? A swift and sharp decline in the share price, followed by further weakness into September.

Short-term pain vs long-term gain

Short-term market reactions can be brutal. However, history shows that quality companies like CSL have often bounced back strongly from periods of doubt as their earnings continue increasing.

The company remains one of the largest and most profitable healthcare groups on the ASX, with deep expertise in plasma-derived therapies, immunology, and rare diseases. Its global reach and heavy investment in research underpin long-term growth prospects.

Brokers remain divided. Macquarie has placed an outperform rating with a $295.90 price target, implying significant upside from current levels. Others, like Sanlam Private Wealth, have opted for a hold stance while the market digests the impact of the demerger.

Why investors are still watching

CSL has long been considered a "market darling" thanks to its enviable track record of compounding growth. Investors who bought CSL two decades ago would be sitting on extraordinary returns today.

Even after the recent fall, CSL commands a premium valuation compared to many ASX 100 peers. That reflects its reputation as a high-quality business with global scale, recurring demand for its therapies, and a pipeline of innovative treatments.

For long-term investors, the current weakness could be seen as a rare chance to add exposure to one of Australia's most successful companies.

Foolish Takeaway

CSL's August tumble was dramatic, but the underlying business continues to grow. The demerger of Seqirus introduces uncertainty, yet it also highlights CSL's willingness to evolve for future growth.

In the short term, volatility may persist. Over the long term, the company's scale, track record, and innovation pipeline remain as compelling as ever.

The Motley Fool Australia's parent company Motley Fool Holdings Inc. has positions in and has recommended CSL and Macquarie Group. The Motley Fool Australia has positions in and has recommended Macquarie Group. The Motley Fool Australia has recommended CSL. The Motley Fool has a disclosure policy. This article contains general investment advice only (under AFSL 400691). Authorised by Scott Phillips.

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