Analyst downgrades AstraZeneca stock due to vaccine side effect concerns

The odds of experiencing a fatal blood clot following inoculation with AstraZeneca's COVID-19 vaccine are less than one in a million, but that was enough to spook Argus Research.

women in a lab carrying out a medical experiment

Image source: Getty Images

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More

This article was originally published on Fool.com. All figures quoted in US dollars unless otherwise stated.

Shares of AstraZeneca (NASDAQ: AZN) are under pressure again following an analyst downgrade. Concerns about the pharmaceutical company's coronavirus vaccine led Argus Research to lower its rating on the stock from buy to hold on Monday morning.

Last Wednesday, the European Medicines Agency (EMA) said unusual blood clots with low blood platelets should be listed as a very rare side effect of AstraZeneca's COVID-19 vaccine, recently given the trade name Vaxzevria. The risk of death from COVID-19 is many orders of magnitude greater, but delays to Vaxzevria's European roll-out had already damaged public opinion regarding it. Across the EU and the U.K., around 34 million people have been vaccinated as of April 4, 2021. Over that period, 222 blood clots were reported to the EMA's side-effect hotline. The vast majority of those were non-fatal.

Vaccine hesitancy in the EU and U.S. is already a problem, and the slightest hint of a dangerous side effect will make it more difficult, if not impossible, for AstraZeneca to earn significant profits from Vaxzevra. That said since the company had already committed to selling the vaccine at cost during the pandemic, and on a permanent not-for-profit basis to low- and middle-income countries, AstraZeneca shareholders don't have much to worry about in terms of lost profits from Vaxzevra over the long run anyway.

The roll-out of this particular COVID-19 vaccine has been a disappointment, but investors need to remember that AstraZeneca isn't a vaccine company. It's an oncology-focused drugmaker and a highly successful one with rapidly rising profits.

Unless cancer patients suddenly begin caring about who markets their therapies, COVID-19 vaccine hesitancy isn't going to appreciably impact AstraZeneca's earnings. The company's product lineup sports a handful of recently approved treatments that could push the company's bottom line and its stock price steadily higher for years to come.  

This article was originally published on Fool.com. All figures quoted in US dollars unless otherwise stated.

Cory Renauer has no position in any of the stocks mentioned. The Motley Fool Australia has no position in any of the stocks mentioned. The Motley Fool has a disclosure policy. This article contains general investment advice only (under AFSL 400691). Authorised by Bruce Jackson.

More on International Stock News

Data Centre Technology
International Stock News

Better Artificial Intelligence (AI) stock for 2026: Nvidia or AMD?

AMD appears to be gaining ground on Nvidia.

Read more »

a smiling picture of legendary US investment guru Warren Buffett.
International Stock News

What Warren Buffett's latest portfolio moves say about the market

Buffett's recent actions tell us something extremely important about the market right now.

Read more »

A family of three sit on the sofa watching television.
International Stock News

3 stocks that in 20 years have turned $5,000 into more than $1 million

These stocks have all soared more than 20,000% in the past 20 years.

Read more »

Happy man working on his laptop.
International Stock News

These 2 magnificent seven AI stocks might be offering investors a once-in-a-decade buying opportunity before the New Year.

These stocks have plenty of room to run.

Read more »

A tech worker wearing a mask holds a computer chip.
International Stock News

Will Nvidia crush the market again in 2026?

The chipmaker has an excellent track record.

Read more »

A man with a wide, eager smile on his face holds up three fingers.
International Stock News

The 3 smartest quantum computing stocks to buy with $1,000 in 2026

While pure plays like IonQ and Rigetti Computing get most of the attention, investors can gain exposure to quantum computing…

Read more »

A woman sits at her computer with her chin resting on her hand as she contemplates her next potential investment.
International Stock News

Alphabet just did something it hasn't done in 7 years. Time to buy?

Alphabet is a key player in the high-growth AI market.

Read more »

Investor kissing piggy bank.
International Stock News

Ranking the best "Magnificent Seven" stocks to buy for 2026. Here's my No. 1 pick.

In today's premium-priced stock market, investors can turn to Microsoft for growth at a compelling value.

Read more »