Up over 1,000%: Can the best-performing stocks on the ASX 200 keep rising?

Analysts tip an upside for both of these ASX 200 shares over the next 12 months. But how much?

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The S&P/ASX 200 Index (ASX: XJO) has had a choppy time over the past 12 months as global volatility, share market uncertainty, interest rate stress, and fickle investors saw shares across the index swing wildly.

At the time of writing, the ASX 200 Index is just over 0.5% higher year to date and around 1% higher than 12 months ago.

Around half of the shares on the index are now trading lower than they were 12 months ago. But, on the flip side, there are some standout performers that have roared higher over the past year.

4DMedical Ltd (ASX: 4DX) and Sunrise Energy Metals Ltd (ASX: SRL) shares have each risen by more than 1,000% over the past 12 months. 

Find out if they can keep climbing higher.

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Are 4DMedical shares a buy, sell, or hold?

4DMedical shares have risen 1,215% over the past 12 months and are trading at $3.42 a piece at the time of writing. The ASX healthcare business is the strongest performer on the ASX 200 Index over the past 12 months.

The company saw its share price explode in 2025 after its flagship product, CT:VQ, received regulatory approvals. It was quickly implemented and adopted through various contracts and partnerships with major hospitals and medical providers, primarily across the US. 

The leap in development and fast adoption means 4DMedical moved very quickly from a research and development business to a globally commercial business.

The share price peaked at an all-time high of $6.80 a piece in April this year. This was when the company joined the ASX 200 Index. 

But the shares quickly shed around 50% after a broad sell-off of ASX 200 healthcare stocks drove many shares across the sector to low levels. It's also likely that many investors rushed to take their gains off the table after an incredible run-up.

Since then, the shares have been relatively flat as investors try to work out whether the business has the potential to keep growing.

4D Medical is still in its growth phase and is working to expand its commercial footprint further. Approvals have been secured in Canada and New Zealand. The company is now actively progressing commercialisation plans in Europe and Australia.

It looks like analysts are divided about the outlook for the shares.

TradingView data shows three analysts are split between strong buy, hold, and strong sell ratings. A $4.97 target price implies a 45% upside at the time of writing. But some think the shares have the potential to jump 75% to $6 a piece over the next 12 months.

Are Sunrise Energy shares a buy, sell, or hold?

Sunrise Energy is not officially a member of the ASX 200. But the company currently ranks in 194th place across all ASX-listed companies (out of 2,336) based on its market capitalisation of $2.4 billion.

Sunrise Energy develops huge mining and mineral processing projects. Essentially, the company develops and manages the application of ion-exchange technology. This technology is used to extract valuable metals for the mining industry and to purify and recycle wastewater.

The Australian minerals company is also developing one of the world's largest and highest-grade primary scandium and nickel-cobalt deposits. Its flagship operation is the Syerston Project in central-west NSW.

This exposure gives Sunrise Energy a unique position in an emerging market where demand is booming, but there aren't many credible suppliers. 

Over the past 12 months, Sunrise Energy shares have climbed by over 1,050%. The shares are trading at $15.42 a piece at the time of writing. The increase has been relatively consistent over that period, too.

The share price spiked at $18.59 in late June and has cooled slightly since then, most likely due to investors taking gains off the table after the huge rally. 

The challenge for investors is that analyst coverage on the stock is limited. TradingView data shows that only one broker currently covers Sunrise Energy. However, that broker has a strong buy rating and a $20 target price on the shares. At the time of writing, that implies a potential 30% upside over the next 12 months.

Motley Fool contributor Samantha Menzies has no position in any of the stocks mentioned. The Motley Fool Australia's parent company Motley Fool Holdings Inc. has no position in any of the stocks mentioned. The Motley Fool Australia has no position in any of the stocks mentioned. The Motley Fool has a disclosure policy. This article contains general investment advice only (under AFSL 400691). Authorised by Scott Phillips.

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