The Motley Fool

Why iSignthis and Opthea shares are up over 400% in 2019

The All Ordinaries index may be up materially this year, but some members of the index have thoroughly outperformed it.

The two best performers on the index this year are listed below. Here’s why they are both up over 400% since the turn of the year:

The iSignthis Ltd (ASX: ISX) share price is the best performer on the All Ordinaries this year with a whopping gain of 545%. It has caught the eye of investors this year thanks to its successful evolution into a wholesale neobank offering digital identity and banking services for regulated businesses and financial institutions in Australia and Europe.

In addition to this, it is the only neobank offering payments, eMoney deposit taking, and identity verification across multiple jurisdictions. These developments have led to many classing it as Australia’s answer to PayPal. Another positive is that unlike many other small cap tech shares, the company expects to be profitable on an operating basis this year. At its last quarterly update iSignthis confirmed its calendar year 2019 EBITDA target of $10.7 million.

The Opthea Ltd (ASX: OPT) share price isn’t far behind iSignthis with a massive 402% gain in 2019. The majority of this gain has come this month thanks to an impressive study update from the developer of novel biologic therapies for the treatment of eye diseases. That study related to its OPT-302 combination therapy for treatment-naïve patients with wet age-related macular degeneration (AMD).

According to the release, OPT-302 (2.0 mg) combination therapy showed statistical superiority for the most accepted and sensitive primary efficacy outcome. This could potentially be a game-changer for the company as the the standard of care treatments for wet AMD and fellow treatment target Diabetic Macular Edema (DME) had sales of over US$3.7 billion and US$6.2 billion, respectively, in 2018.

Looking for the next iSignthis and Opthea? Then check out this hot mid cap growth stock which has a massive US$22 billion market opportunity and was recently rated as a buy.

One ASX Stock For An Estimated $US22 Billion Marijuana Market

A little-known ASX company just unlocked what some experts think could be the key to profiting off the coming marijuana boom.

And make no mistake – it is coming. To the tune of an estimated $US22 billion.

Cannabis legalisation is sweeping over North America, and full legalisation arrived in Canada in October 2018.

Here's the best part: we think there's one ASX stock that's uniquely positioned to profit immensely from this explosive new industry... taking savvy investors along for what could be one heck of a ride.

AND, this is the first time The Motley Fool Australia has EVER put a BUY recommendation on a marijuana stock.

Simply click below to learn more on how you can profit from the coming cannabis boom.

Click here to find out more

Motley Fool contributor James Mickleboro has no position in any of the stocks mentioned. The Motley Fool Australia has no position in any of the stocks mentioned. We Fools may not all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors. The Motley Fool has a disclosure policy. This article contains general investment advice only (under AFSL 400691). Authorised by Scott Phillips.

FREE REPORT: Five Cheap and Good Stocks to Buy now…

Our Motley Fool experts have FREE report, detailing 5 dirt cheap shares that you can buy today.

One stock is an Australian internet darling with a rock solid reputation and an exciting new business line that promises years (or even decades) of growth… while trading at an ultra-low price…

Another is a diversified conglomerate trading near a 52-week low all while offering a 2.7% fully franked yield…

Plus 3 more cheap bets that could position you to profit over the next 12 months!

See for yourself now. Simply click the link below to scoop up your FREE copy and discover all 5 shares. But you will want to hurry – this free report is available for a brief time only.